LymphedemaV1, Main, Exploration, bibRecord, 002239

A Randomized Controlled Trial of Outpatient CAncer REhabilitation for Older Adults: The CARE Program

Identifieur interne : 002239 ( Main/Exploration ); précédent : 002238; suivant : 002240

A Randomized Controlled Trial of Outpatient CAncer REhabilitation for Older Adults: The CARE Program

Auteurs : Mackenzi Pergolotti [États-Unis] ; Allison M. Deal [États-Unis] ; Grant R. Williams [États-Unis] ; Ashley L. Bryant [États-Unis] ; Bryce B. Reeve [États-Unis] ; Hyman B. Muss [États-Unis]

Source :

Contemporary clinical trials [ 1551-7144 ] ; 2015.

RBID : PMC:4740286

Abstract

Background

Large numbers of older adults (aged 65 years or older) are surviving cancer; however, many survivors report decreased quality of life (QOL) and limitations in activities of daily living (ADL) and instrumental activities of daily living (IADL) both during and after treatment [1–3]. Occupational and physical therapy (OT/PT) are services focused on improving functional status and QOL that are largely unexplored and underutilized in cancer survivorship care [4, 5].

Methods/Design

This is a randomized, single-blind, two-arm, single institution pilot study. Eighty-two patients will be recruited from a university-affiliated outpatient oncology clinic. Inclusion criteria include the following: aged 65 years or older, diagnosis of cancer within 5 years, English speaking, has at least one functional deficit, and able to safely participate in an outpatient rehabilitation program. Exclusion criteria are: currently receiving rehabilitation or eligible for hospice. Consented patients will be randomized into two groups: (1) the CARE (CAncer REhabilitation) Program consisting of outpatient OT/PT and (2) standard of care. Primary outcome: change in Nottingham Extended Activities of Daily Living (NEADL) scores from baseline to 3 months between CARE and control.

Discussion

This study is one of the first RCTs aimed at examining the effect of OT/PT in older adults with cancer. If positive, findings from this study will suggest the potential for outpatient OT/PT to improve the functional ability and QOL of older adults with cancer.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740286

DOI: 10.1016/j.cct.2015.07.021
PubMed: 26253182
PubMed Central: 4740286

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">Large numbers of older adults (aged 65 years or older) are surviving cancer; however, many survivors report decreased quality of life (QOL) and limitations in activities of daily living (ADL) and instrumental activities of daily living (IADL) both during and after treatment [<xref rid="R1" ref-type="bibr">1</xref>
–<xref rid="R3" ref-type="bibr">3</xref>
]. Occupational and physical therapy (OT/PT) are services focused on improving functional status and QOL that are largely unexplored and underutilized in cancer survivorship care [<xref rid="R4" ref-type="bibr">4</xref>
, <xref rid="R5" ref-type="bibr">5</xref>
].</p>
</sec>
<sec id="S2"><title>Methods/Design</title>
<p id="P2">This is a randomized, single-blind, two-arm, single institution pilot study. Eighty-two patients will be recruited from a university-affiliated outpatient oncology clinic. Inclusion criteria include the following: aged 65 years or older, diagnosis of cancer within 5 years, English speaking, has at least one functional deficit, and able to safely participate in an outpatient rehabilitation program. Exclusion criteria are: currently receiving rehabilitation or eligible for hospice. Consented patients will be randomized into two groups: (1) the CARE (CAncer REhabilitation) Program consisting of outpatient OT/PT and (2) standard of care. Primary outcome: change in Nottingham Extended Activities of Daily Living (NEADL) scores from baseline to 3 months between CARE and control.</p>
</sec>
<sec id="S3"><title>Discussion</title>
<p id="P3">This study is one of the first RCTs aimed at examining the effect of OT/PT in older adults with cancer. If positive, findings from this study will suggest the potential for outpatient OT/PT to improve the functional ability and QOL of older adults with cancer.</p>
</sec>
</div>
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<name sortKey="Bryant, Ashley L" sort="Bryant, Ashley L" uniqKey="Bryant A" first="Ashley L." last="Bryant">Ashley L. Bryant</name>
<name sortKey="Deal, Allison M" sort="Deal, Allison M" uniqKey="Deal A" first="Allison M" last="Deal">Allison M. Deal</name>
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<name sortKey="Williams, Grant R" sort="Williams, Grant R" uniqKey="Williams G" first="Grant R." last="Williams">Grant R. Williams</name>
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A Randomized Controlled Trial of Outpatient CAncer REhabilitation for Older Adults: The CARE Program

A Randomized Controlled Trial of Outpatient CAncer REhabilitation for Older Adults: The CARE Program

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